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Genomics

Researchers Detail New Data in Business: Genome Assembly of Chinese Herbal Medicine Chelidonium Majus

Strategic Insights

— 1 min read

Chinese herbal medicine Chelidonium majus has been found to possess significant medicinal value, with its genome remaining uncharacterized until now. A team of researchers from China Three Gorges Corporation has successfully assembled a high-quality chromosome-scale genome for C. majus, providing a vital resource for future gene screening, drug discovery, and pharmacological exploration. The genome assembly is notable for its size of 1.06 Gb, with 91.21% of sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb.

Key Takeaways:

  • A high-quality chromosome-scale genome assembly of Chelidonium majus, a Chinese herbal medicine, has been completed by researchers from China Three Gorges Corporation.
  • The genome assembly consists of 1.06 Gb, with 91.21% of sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb.
  • The genome is predicted to contain 25,203 protein-coding genes, with 98.2% of them functionally annotated.
  • The completeness of the genome is validated by a BUSCO score of 97.6%.
  • This genome assembly provides a vital resource for future gene screening, drug discovery, and pharmacological exploration in C. majus.
  • Authors of the study include Yu Zhao, Hubei Key Laboratory of Three Gorges Project for Conservation of Fishes, Chinese Sturgeon Research Institute, China Three Gorges Corporation, and 9 other researchers.
  • The study aimed to provide a comprehensive understanding of the C. majus genome, which is essential for its medicinal applications.

Statistics:

  • Genome size: 1.06 Gb
  • Sequences anchored onto 6 chromosomes: 91.21%
  • Number of contigs: 1,520
  • N50: 106.65 Mb
  • Protein-coding genes: 25,203
  • Functional annotation: 98.2%
  • BUSCO score: 97.6%
  • Size of chromosome-scale genome assembly: 1.06 Gb

Sources:

  • A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus. Scientific Data, 2025, 12(1): 1-8. (Scientific Data - https://www.nature.com/sdata/)
  • NewsRx. New Findings in Business Described from China Three Gorges Corporation (A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus). Life Science Weekly. November 4, 2025; p 3001.

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