Researchers Develop New Method for Synthesizing Antibacterial Nanoparticles
Researchers at Gubkin University have developed a novel method for synthesizing nanocomposites with silver nanoparticles and organic acids, which could have significant implications for the development of antibacterial coatings. According to a study published in the Chimica Techno Acta journal, the researchers found that a synergistic effect was achieved by combining metal ions and acid, resulting in a more effective antibacterial agent. The study concluded that the largest diameter of the growth inhibition zones of Staphylococcus aureus (MRSA 45) was achieved with sorbic acid, with a diameter of 13-15 mm.
Key Takeaways:
- The researchers developed a method for synthesizing nanocomposites with silver nanoparticles and sorbic acid or 4-hydroxybenzoic acid as components of antibacterial coatings.
- A synergistic effect was found by combining two biocides (metal ions and acid), resulting in a more effective antibacterial agent.
- The application of the developed synthesis technique made it possible to obtain silver nanoparticles with a particle size distribution of 1-6 nm on halloysite and up to 10 nm on sepiolite.
- Using thermogravimetric analysis, it was found that the maximum loading of acids into carrier pairs is observed at the carrier:acid ratio of 1:1.
- The release of sorbic acid and 4-hydroxybenzoic acid from the pores of halloysite and sepiolite in an aqueous medium was observed for 150-200 min.
- The researchers concluded that the largest diameter of the growth inhibition zones of Staphylococcus aureus (MRSA 45) was achieved with sorbic acid, with a diameter of 13-15 mm.
- The study suggests that the developed method could be used to create effective antibacterial coatings for medical devices or other applications.
Statistics:
- The release of acids from the pores of halloysite and sepiolite in an aqueous medium was observed for 150-200 min.
- The maximum loading of acids into carrier pairs is observed at the carrier:acid ratio of 1:1.
- The silver nanoparticles had a particle size distribution of 1-6 nm on halloysite and up to 10 nm on sepiolite.
- The largest diameter of the growth inhibition zones of Staphylococcus aureus (MRSA 45) was achieved with sorbic acid, with a diameter of 13-15 mm.
Sources:
- VerticalNews, "New Findings in Nanoparticles Shed Light on Development of Antibacterial Coatings" (2025, October 27)
- Chimica Techno Acta, "Antibacterial properties of biocides based on silver nanoparticles and organic acids" (2025, 12(3))
- Gubkin University, Research Group, "Development of Antibacterial Coatings Using Silver Nanoparticles and Organic Acids" (2025)
- NewsRx, "Researchers' from Gubkin University Report Details of New Studies and Findings in the Area of Nanoparticles" (2025, October 27, p 4161)