Residual Antimicrobial Coating Efficacy Against SARS-CoV-2

Research conducted at the US Environmental Protection Agency (EPA) has evaluated the efficacy of commercially available antimicrobial coatings or films against the SARS-CoV-2 virus on non-porous surfaces. Products were tested on stainless steel and ABS plastic coupons, with varying concentrations of 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride showing the most effective results. The study highlights the need for product-specific efficacy in combating SARS-CoV-2, as differences in observed efficacy may be due to variation in active ingredient formulation.

Key Takeaways:

  • Researchers evaluated 12 commercially available antimicrobial coatings or films against SARS-CoV-2 on non-porous surfaces.
  • Products were tested on stainless steel and ABS plastic coupons, with varying concentrations of 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride showing the most effective results.
  • The study found that the residual antimicrobial products tested showed varied effectiveness against SARS-CoV-2 as a function of product tested.
  • Differences in observed efficacy may be due to variation in active ingredient formulation.
  • The most effective products tested contained varying concentrations (0.5%-1.3%) of 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride.
  • Products formulated with other quaternary ammonium compounds were less effective against SARS-CoV-2 in this test.
  • Several products were identified as efficacious against SARS-CoV-2 on both stainless steel and ABS plastic surfaces under the conditions evaluated.

Statistics:

  • 12 commercially available antimicrobial coatings or films were tested against SARS-CoV-2.
  • The products tested on stainless steel showed a log (10) reduction in recovered infectious SARS-CoV-2 ranging from 0.44 to 3 log (10).
  • The products tested on ABS plastic showed a log (10) reduction in recovered infectious SARS-CoV-2 ranging from 0.25 to 1.67 log (10).
  • The most effective products tested contained varying concentrations (0.5%-1.3%) of 3-(trihydroxysilyl) propyldimethyloctadecyl ammonium chloride.

Sources:

  • Residual Antimicrobial Coating Efficacy Against Sars-cov-2. Journal of Applied Microbiology, 2022.
  • Wiley, 111 River St, Hoboken 07030-5774, NJ, USA (www.wiley.com/; onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2672)