Rheumatoid factor
Researchers at Fujian Medical University have conducted a study to assess the association between tofacitinib use and the risk of venous thromboembolism (VTE) events in patients with rheumatoid arthritis (RA). The study, published in Naunyn-Schmiedeberg's Archives of Pharmacology, found that tofacitinib was associated with a significantly elevated risk
Antirheumatic agents
Newcastle University researchers have made a groundbreaking discovery in the treatment of rheumatoid arthritis, finding that an anti-rheumatic drug can reverse muscle wasting in patients. The study, published in The Lancet Rheumatology, involved 15 patients with rheumatoid arthritis who were given Tofacitinib, a Janus kinase (JAK) inhibitor. After six months,
Diseases
A new study conducted by researchers at Wuhan 1 Hosp, Dept. of Rheumatology and Immunology, has found that leucine-rich alpha-2-glycoprotein 1 (LRG1) may play a role in the supervision of rheumatoid arthritis (RA) disease. The study, published in Clinical Rheumatology, aimed to investigate the correlation of serum LRG1 level with
Diseases
Recent research conducted at the University of Messina has highlighted the significance of mitochondria in the onset and progression of rheumatoid arthritis (RA). The study, published in Biomedicines, discusses the role of mitochondria in the physiopathology of RA, contributing to chronic inflammation, cartilage and bone injury, and chronic autoimmune response.
Diseases
Researchers have discovered that macrophages play a key role in regulating inflammatory and fibrotic processes in several autoimmune and inflammatory rheumatic diseases. Macrophages are highly plastic cells that can shift between pro-inflammatory and anti-inflammatory phenotypes in response to environmental factors and cytokine signatures. This plasticity is enhanced in synovial tissue
Diseases
Researchers at the University of Gothenburg have conducted an exploratory metabolomic profiling study in the NORD-STAR cohort to identify biomarkers for treatment response in early rheumatoid arthritis. The study, which included 220 early RA participants, aimed to profile serum metabolic alterations associated with disease activity and therapeutic response. The findings
Diseases
People with arthritis are often told to consider making lifestyle changes as a way to alleviate their symptoms, but many are skeptical. However, experts agree that these changes can significantly improve quality of life for those suffering from the condition. With over 10 million people in the UK now living
Arthritis
Knee braces have emerged as the most effective way to alleviate symptoms of osteoarthritis, a degenerative joint disease affecting 33 million U.S. adults, according to a recent study published in PLOS One. The meta-analysis, led by Yuan Luo, a researcher in the department of rehabilitation at the First People&
Antiarthritic agents
A recent multicenter, retrospective study published in the journal Rheumatology has shed light on the sustained efficacy of second-line Janus kinase (JAK) inhibitors in patients with rheumatoid arthritis (RA). The study, conducted by researchers at Osaka University, analyzed data from an observational multicenter registry of patients with RA in Japan,
Arthritis
Research conducted at the University of Ferrara has shed light on the risk of cardiovascular events (CVEs) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis). The study aimed to compare the risk of CVEs in RA patients treated with JAKis or
