Cancer
Gastric cancer remains one of the most common and deadly cancer types worldwide. Researchers from the Federal University of Sao Paulo have identified two minimally invasive biomarkers in peripheral blood that can be used for gastric cancer detection and postoperative monitoring. The study, published in In Vivo, found that expression
Cancer
Researchers at Tianjin Medical University General Hospital have reported a potential immunotherapeutic target for gastric cancer, revealing a novel role of EBI3 in promoting CD8+ T cell exhaustion and compromising the effectiveness of immunotherapy. The study highlights the correlation between EBI3 expression levels and clinical-pathological features of gastric cancer, including
Cancer
Advanced sarcomas, a rare and aggressive type of cancer, have limited treatment options. Researchers from Shandong Cancer Hospital in China investigated the efficacy and safety of combining sintilimab and anlotinib, two immunotherapies, in treating advanced sarcomas. The study involved 42 patients with untreated or chemotherapy-resistant sarcomas. The combination treatment resulted
Cancer
Researchers at Hokkaido University in Sapporo, Japan, have made a crucial discovery regarding the effects of radiation therapy on cancer cell migration. According to their study, published in the International Journal of Molecular Sciences, radiation-induced bystander effects can inadvertently enhance tumor cell motility outside the target volume. This finding has
Cancer
Cancer screening rates among older Medicaid enrollees in New Jersey have been significantly impacted by provider and organizational factors during the COVID-19 pandemic. According to recent research, higher patient panel sizes and obstetrician-gynecologist providers have been associated with increased screening rates for breast, cervical, and lung cancers. Additionally, female providers
Cancer
A recent study conducted by researchers at the Medical University Innsbruck in Innsbruck, Austria, has revealed an exceptional prognosis in POLE-mutated endometrial cancers, even in the presence of brain metastases. According to the research, patients with POLE-mutated endometrioid ECs and brain metastases have survived substantially longer than the median survival
Cancer
A recent multi-institutional study has analyzed 39 cases of anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL), a rare and aggressive subtype of diffuse large B-cell lymphoma with poor outcomes using standard chemotherapy. Researchers from the University of Texas MD Anderson Cancer Center found that despite conventional cytotoxic regimens, outcomes
Cancer
Lipid nanoparticles, a revolutionary technology, have been rapidly advancing the field of cancer gene therapy. A recent study from Fudan University in Shanghai, China, has highlighted the potential of these nanoparticles in delivering RNA therapeutics, leading to breakthroughs in the treatment of various diseases, including cancer, HIV, and malaria. The
Cancer
Researchers at the Tianjin Medical University Cancer Institute and Hospital have developed a novel solid phase extraction (SPE) method using hydrophobic polypropylene fabric (PPF) for the accurate quantification of tyrosine kinase inhibitors (TKIs) in plasma. This method enables sensitive determination of eight clinically relevant TKIs in plasma, with high extraction
Cancer
Researchers at Chongqing University Cancer Hospital have developed a machine learning-based early warning system to predict venous thromboembolism (VTE) in lymphoma patients undergoing chemotherapy. The system, known as VTE-EWS, uses 12 clinical variables and six machine learning algorithms to identify patients at high risk of VTE. According to a new
Cancer
A recent study published in BJC Reports has shed light on the critical factors that impact patient recruitment in phase I oncology trials. Researchers from the Institute of Cancer Research conducted a retrospective study involving 1671 patients, finding that polypharmacy and comorbidity have a significant association with trial recruitment, time
Cancer
A recent study by researchers from Duke University has shed light on the disparities in cancer outcomes among patients from low socioeconomic status neighborhoods in the United States. The study, which analyzed data from 266,269 hospital admissions, found that patients from neighborhoods with lower socioeconomic status had higher mortality
