The Advisory Committee on Immunization Practices (ACIP): Governance, Recommendations, and Impact

The Advisory Committee on Immunization Practices (ACIP) plays a critical role in shaping the nation's vaccine policies and recommendations. The committee, established in 1964, consists of experts who provide crucial advice to the Department of Health and Human Services (HHS) on vaccine use and related agents for the control of vaccine-preventable diseases. ACIP's recommendations inform the Centers for Disease Control and Prevention's (CDC) annual immunization schedules and have significant implications for public health policy.

Key Takeaways:

  • The ACIP is a critical committee that provides expert advice to HHS on vaccine use and related agents, informing the CDC's annual immunization schedules.
  • The committee has a long history, dating back to 1964, and has undergone several changes, including the removal of 17 members in June 2025 and the appointment of new members.
  • ACIP's recommendations are based on available evidence and consider factors such as the benefits of recommending a vaccine, potential harms, and public health importance.
  • The committee holds public meetings at least three times a year and serves on work groups to review evidence regarding specific vaccines.
  • ACIP's recommendations are categorized into two types: Standard Recommendations and Shared Clinical Decisionmaking.
  • The CDC Director reviews and decides whether to formally adopt ACIP's recommendations, which are published in the CDC Morbidity and Mortality Weekly Report.
  • Immunization schedules have undergone changes in recent years, with the 2025 schedule being updated to reflect new recommendations.
  • ACIP plays a crucial role in defining statutory requirements, such as the Vaccines for Children (VFC) program and health care coverage.
  • State laws may direct the use or consideration of ACIP recommendations in various circumstances, including immunization requirements and vaccine coverage.

Statistics:

  • ACIP has made recommendations for over 50 percent of vaccines currently in use.
  • The committee typically holds three public meetings per year, with each meeting lasting around 2-3 days.
  • ACIP's work groups consist of two voting members, a CDC subject matter expert, and nonvoting liaison representatives from national health organizations.
  • As of 2025, ACIP has 17 voting members and 5 nonvoting representatives.
  • The 2025 immunization schedule recommends 23 vaccines for routine use in children and 16 vaccines for adults.
  • ACIP's recommendations have been followed in over 90 percent of cases.

Sources:

  • Congressional Research Service, "Advisory Committee on Immunization Practices (ACIP) in Focus" (CRS-2025-IF12317)
  • Association of State and Territorial Health Officials, "ACIP Laws and Regulations Review" (2025)
  • Centers for Disease Control and Prevention, "Morbidity and Mortality Weekly Report" (2025)
  • Social Security Act, Section 1928 (42 U.S.C. Sec.1396s)
  • 21st Century Cures Act of 2016 (P.L. 114-255, as amended, Sec.3091)