The Rise of a "Superbug" in New Zealand: How Antibiotic Use Fuelled Its Spread
The spread of methicillin-resistant Staphylococcus aureus (MRSA) has become a pressing concern in New Zealand, with the country's antibiotic-dispensing habits significantly contributing to the emergence and spread of the "superbug". The New Zealand-born strain, AK3, has been detected in the South Pacific and Europe, and its rapid expansion is linked to the overuse of topical fusidic acid in the past. Research has shown that AK3 is more prevalent among Mýüori and Pacific peoples, and those in deprived areas are more likely to be hospitalized with skin infections.
Key Takeaways:
- The New Zealand-born strain, AK3, has spread to the South Pacific and Europe, making it a globally significant resistance.
- The use of topical fusidic acid in New Zealand contributed to the emergence and spread of AK3, with dispensing peaking in 2013 and declining after 2016.
- AK3 is more prevalent among Mýüori and Pacific peoples, with those in deprived areas being nearly four times more likely to be hospitalized with skin infections.
- The emergence of AK3 highlights the need for a proactive approach to antimicrobial resistance, integrating surveillance with coordinated policy and action across human, animal, and environmental domains.
- Genomics is a key strategic priority in supporting an evidence-based approach to current and emerging diseases.
Statistics:
- AK3 was first detected in 2005, and by 2009, it had become the dominant strain in New Zealand.
- The peak dispensing of topical fusidic acid in 2013 contributed to the spread of AK3.
- AK3 has been detected in the South Pacific and Europe, with 3 times more likely incidence in Mýüori and 5 times more likely in Pacific peoples.
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Sources:
- The Conversation (Au and NZ) -- By Rhys Thomas White, Scientist in Genomics and Bioinformatics, New Zealand Institute for Public Health and Forensic Science
- Getty Images
- Oxford Nanopore Technologies
- Genomics Aotearoa
- The Conversation - Antibiotic use likely fuelled the rise of a 'superbug' in NZ -- genomics offers a defence against the next threat - Ref: https://theconversation.com/antibiotic-use-likely-fuelled-the-rise-of-a-superbug-in-nz-genomics-offers-a-defence-against-the-next-threat-262316