Addressing Antimicrobial Resistance through a Regional One Health Approach

Research from the University of Greifswald highlights the importance of addressing antimicrobial resistance (AMR) as a One Health problem that requires systemic thinking and coordinated networking between different levels of society and regional institutions. The study identifies key leverage points, including interdisciplinary and intersectoral collaboration, homogeneity of data, and public awareness, to address AMR in a regional context. The research concludes that a participatory systems thinking approach can be effective in mapping antimicrobial resistance interactions in a One Health region.

Key Takeaways:

  • Antimicrobial resistance (AMR) is a One Health problem that requires a systemic thinking approach and coordinated networking between different levels of society and regional institutions.
  • A regional One Health approach can be an effective strategy to address AMR, as it involves participatory systems thinking and integrates human, animal, and ecological components.
  • The study identified two amplifying and two balancing loops in the model, covering antibiotic stewardship, public awareness, regional data management, and environmental impact.
  • Interdisciplinary and intersectoral collaboration, homogeneity of data, and public awareness were identified as important leverage points to address AMR in a regional context.
  • The study concludes that a participatory systems thinking approach can provide an opportunity to identify and visualize important risk factors that are direct or indirect drivers of AMR.
  • The research highlights the importance of engaging regional stakeholders in the data collection and modeling process to ensure effective management of AMR.
  • The study emphasizes the need for a deeper understanding of regional resistance patterns and the rational use of antibiotics from a One Health perspective.

Statistics:

  • The study found that the system mapping tool is suitable for demonstrating the relationships regarding AMR in the One Health context for a defined region.
  • The research identified two amplifying loops and two balancing loops in the model, covering key areas of antibiotic stewardship, public awareness, data management, and environmental impact.
  • The study applied leverage point analysis to estimate the types of interventions that would have the greatest ability to address AMR in the One Health region.
  • The research involved participatory data collection and modeling processes through surveys, semi-structured interviews, and interactive workshops.

Sources:

  • VerticalNews. New research on Environment from Universitat Greifswald (2025 OCT 24)
  • A regional One Health approach to mapping antimicrobial resistance interactions via systems thinking. One Health Outlook, 2025;7(1):46.
  • NewsRx. New Environment Findings from University of Greifswald Reported (A regional One Health approach to mapping antimicrobial resistance interactions via systems thinking). Ecology, Environment & Conservation. October 24, 2025; p 554.