Salinity Stress Enhances Inhibitory Activity in Mulberry Leaves
Research conducted by scientists from Atma Jaya Catholic University of Indonesia has shown that salinity stress enhances the inhibitory activity of mulberry leaf extracts against the a-glucosidase enzyme. The study, published in the Hayati Journal of Biosciences, found that high salinity stress increases the accumulation of phenolic and flavonoid compounds in mulberry leaves, leading to enhanced inhibitory potential against the enzyme. The researchers identified a particular sample, MB2-3, which exhibited the most favorable IC50 value and substantial phenolic and flavonoid content.
Key Takeaways:
- Salinity stress disrupts redox homeostasis in plants, leading to notable changes in the levels of bioactive compounds, including phenolic and flavonoid compounds.
- High salinity stress enhances the inhibitory activity of mulberry leaf extracts against the a-glucosidase enzyme.
- The MB2-3 sample exhibited the most favorable IC50 value (0.59 g/mL), coupled with a substantial phenolic content (141.9 mg GAE/g extract) and the highest content of flavonoid observed among all tested samples (619.56 mg QE/g extract).
- The inhibitory potential of mulberry extracts against a-glucosidase is modulated by salinity stress, leading to enhanced antioxidant activity and accumulation of phenolic and flavonoid compounds.
- The study highlights the capacity of salinity stress to augment the inhibitory potential of mulberry extracts against a-glucosidase and the accumulation of phenolic and flavonoid compounds.
- The findings of this study have potential implications for the development of natural products with glycemic control properties.
Statistics:
- IC50 value of MB2-3 sample: 0.59 g/mL.
- Phenolic content of MB2-3 sample: 141.9 mg GAE/g extract.
- Flavonoid content of MB2-3 sample: 619.56 mg QE/g extract.
- Total flavonoid content of all tested samples: range of 12.3-619.56 mg QE/g extract.
- Total phenolic content of all tested samples: range of 5.2-141.9 mg GAE/g extract.
- Salinity stress level: high (up to 10% NaCl solution).
Sources:
- Hayati Journal of Biosciences - http://journal.ipb.ac.id/index.php/hayati
- (Hayati Journal of Biosciences - doi: 10.4308/hjb.33.1.87-94)